
Active Folate. Active B12.
9 Actives. One Capsule. 120 Days.
5-MTHF (Quatrefolic®) 1mg + Methylcobalamin B12 1mg + B6 (P-5-P) 20mg + B2 (R-5-P) 20mg + Niacin 50mg + Pantothenic Acid 50mg + Biotin 1000µg + Organic Spirulina 150mg + Organic Beetroot 100mg. Active B-vitamin forms throughout. Vegan Pullulan capsule. Made in the UK.
9 actives including Quatrefolic® 4th-generation methylfolate — 120 capsules, 120-day supply
What's Inside
Is Everything.

5-MTHF (Quatrefolic®, Active Folate)
1mg of 5-MTHF (5-methyltetrahydrofolate) per capsule, provided as Quatrefolic® — the 4th-generation L-methylfolate. Unlike synthetic folic acid which requires conversion by the MTHFR enzyme, 5-MTHF is the bioactive, methylated form of folate that is directly utilised by the body. Quatrefolic® is bound to glucosamine for superior stability and bioavailability. Folate contributes to normal homocysteine metabolism, normal psychological function, normal immune function, and the reduction of tiredness and fatigue.*

Vitamin B12 (Methylcobalamin)
1mg methylcobalamin — the active, methylated form of B12, directly utilised without hepatic conversion.*

Vitamin B6 (Pyridoxal-5-Phosphate)
20mg P-5-P — the active coenzyme form of B6, directly available without hepatic phosphorylation.*

Vitamin B2 (Riboflavin-5-Phosphate)
20mg R-5-P — the active phosphorylated form of riboflavin, the rate-limiting cofactor for B6 and folate activation.*

Niacin (Nicotinamide, Vitamin B3)
50mg nicotinamide — the non-flushing amide form of niacin, a precursor to NAD+ and NADP+.*

Pantothenic Acid (Vitamin B5, Calcium Pantothenate)
50mg pantothenic acid — required for the synthesis of coenzyme A (CoA), central to the citric acid cycle.*

Biotin (Vitamin B7)
1000µg biotin — a key cofactor for five carboxylase enzymes involved in fatty acid synthesis, amino acid metabolism, and gluconeogenesis.*

Organic Spirulina Powder (Arthrospira platensis)
150mg organic spirulina — a blue-green microalgae naturally containing phycocyanin, chlorophyll, gamma-linolenic acid, and a broad micronutrient profile.*

Organic Beetroot Powder (Beta vulgaris)
100mg organic beetroot powder — a natural source of dietary nitrates, betaine (TMG), betalain pigments, and folate.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Not Just Folate.
The Active B-Complex.
Quatrefolic® 5-MTHF + Methylcobalamin B12 + active B6, B2, B3, B5 + Biotin + Organic Spirulina + Organic Beetroot. Nine actives. One capsule. 120-day supply.
What the Active B-Complex Feels Like.
Quatrefolic® 5-MTHF + active B12, B6, B2, B3, B5 + Biotin + Spirulina + Beetroot. One capsule a day. 120 days per pouch.
Complete Your Stack.
Customers who buy 5-MTHF Complex most often add these to their routine.
D3 + K2 Softgels — 10,000 IU with Coconut Oil
High-strength vitamin D3 with MK-7 K2 in coconut oil. A great addition to any daily routine.*
300 Billion CFU Probiotic & Prebiotic
Multi-strain synbiotic with digestive enzymes. A great addition to any daily routine.*
Magnesium Glycinate Complex — 6 Forms
6-form magnesium complex with Vitamin B6, Zinc, and BioPerine. A great addition to any daily routine.*
Discount applied automatically at checkout. Cannot be combined with other codes.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Frequently Asked.
Everything you need to know before you start.
A 9-ingredient supplement featuring 5-MTHF (Quatrefolic®), Vitamin B12 (Methylcobalamin), Vitamin B6 (Pyridoxal-5-Phosphate) & more. 60 capsules, 30-serving supply.
Anyone looking to add a comprehensive supplement to their daily wellness routine. Not intended for pregnant or nursing women — consult your healthcare provider if you have a medical condition.
Every batch is third-party lab tested for potency, purity, and contaminants. Manufactured in GMP-certified facilities. Zero artificial fillers, binders, or synthetic additives.
Many customers combine this with other PURETREX products as part of their daily stack. If you're on prescription medication, check with your healthcare provider first.